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How Does Adderall for Depression Affect your Body?




Adderall for depression may serve as a utility drug or medication for ADHD, a hyperactive disorder where a person craves attention.

A study in 1992 published in the Clinical Neuroscience Dialogues reported that the use of stimulants such as Adderall and other traditional forms of antidepressants as a medication for the treatment of depression might have a beneficial output.

However, the same study suggests that only half of those involved in the study improved significantly.

Taking Adderall for depression may be more of a contributing factor for depression, which is regarded as a withdrawal symptom or side effect of the stimulant drug.

It is worthy of note that Adderall is classified as a drug that is often abused by athletes, college students, and workers who depend on it to enhance their capability.

However, conventional antidepressants may be a suitable medication for persons who may be suffering from depression.

While Adderall is used as an(ADHD) medication, and for patients who may be depressed, the use of traditional antidepressants may be more effective.

In this article, we shall center on the effects of Adderall in treating depression, what Adderall is all about, its use and non-suitability for treating depression.

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We shall also highlight the dangers of using this stimulant to treat persons with depression. And also find out the meaning of depression, treatment, psychosis, treatment, and overdose.

What does Adderall mean?

Adderall compromises of four different types of amphetamine salts. These four amphetamine salts include;

  • Amphetamine sulfate
  • Dextroamphetamine saccharate
  • Dextroamphetamine sulfate, and
  • Dextroamphetamine aspartate.

In 1996, the FDA in the United States approved these essential Adderall salts as a treatment for children with narcolepsy and ADHD.

Physicians also recommend Adderall for adults who may also be experiencing narcolepsy or ADHD challenges.

Adderall can provide relief for people with ADHD symptoms when taken in the form of capsules or tablets. Such symptoms include fidgeting, hyperactivity, disorganization, and lack of focus.

Adderall can also reduce the effect of other symptoms. Such as impulsivity and hyperactivity by improving attention and focus.

Adderall for depression treatment may be accomplished by increasing dopamine and norepinephrine levels. It also helps to ramp up the activities of the brain.

Also, Adderall may serve as a drug that stimulates the body’s central nervous system.

Adderall for Depression


Adderall is an off label prescription drug for individuals who experience depression.

A report by a daily mental health magazine suggested that people with ADHD and depression may feel relieved when administered with Adderall drugs.


Research has proven that Adderall is one of the viable and effective single treatment options.

There are several reasons why people may opt for the treatment of depression using Adderall.

These include the following:

1. Increase in confidence

Adderall is known to serve as a confidence boost for working professionals, athletes, and others who may be experiencing low self-esteem.

Since Adderall is a stimulant, it may be able to achieve this.

Young people often abuse Adderall because of its effect in boosting confidence.

Like alcohol, some people may love to be able to carry out daring tasks without the feeling of shyness or self-restraint.

2. Increased energy levels

Adderall for depression may be useful in increasing energy levels since it is a stimulant.

People who are depressed may find it challenging to carry out their routine daily tasks because they may feel less enthusiastic about doing anything.

People with depression may experience both mental and emotional discomfort that may drive down their zeal to work or lead healthy lives.

However, by taking Adderall medication, they may feel much better.

3. Improvement of focus

Since Adderall may provide a boost in confidence and an improved energy level, it may also help individuals with difficulty in maintaining focus to be able to do so effectively.

It may stimulate the brain to be able to pay close attention to details.


You may have better mental alertness with an increased potential to be more efficient in your daily performance.

4. Instant mood improvement

People with depression are often known to exhibit a poor state of mind. They may show signs of sadness, anger, regret, guilt, etc. Such a mood may limit their performance in several areas of their lives.

You may experience difficulty in focusing or engaging in any form of physical activity properly.

They may become very withdrawn and isolate themselves from others. Taking Adderall may help to provide immediate improvement of mood in depressed individuals.

They may be able to feel lighter, less sad, and more willing to communicate with others. However, the individual may also need to visit a therapist for mental evaluation and counseling.

5. Increased level of sociability

We have seen that mood swings, social isolation, and withdrawal symptoms are common among depressed people.

They tend to break off communication with people and may find solace in staying alone.

These individuals may become suicidal, especially if they become more withdrawn from the realities around them.

Adderall has been known to promote sociability in depressed individuals by increasing their energy level, promoting good mood, and improving their ability to maintain focus.

Reasons why Adderall may not be suitable for treating depression

We have seen the effectiveness of Adderall for depression treatment. However, medical experts have warned about the dangers of using Adderall as a medication for depression.


The daily mental health magazine has given the following reasons why Adderall should not be used to treat depression.

#1 Addiction and Abuse

Just like other stimulants, people may abuse this drug. They may take it even when they are not depressed, and can probably take an overdose of it just to enjoy the feelings of highness.

The potential to become addicted to Adderall is very high because some people with depression may not want to find any other workable solution for their issue other than resulting in the intake of Adderall.

The effect of Adderall overdose is one that is more likely to occur in individuals who are addicted to the drug.

#2 Using Adderall for depression may not be a permanent solution

Adderall may not be a permanent solution to depression. The question is, what happens when the effects of Adderall may have worn off.

Will the underlying cause of depression still be there? Of course, it may. You may feel relieved, just like any other stimulant.

Some people who result in taking cannabis or alcohol when they are depressed may feel out of their predicament for some time.

But may suddenly find themselves staring at the reality of their situation when their effect may have worn off.

#3 Adderall users may be quick to develop a tolerance for the drug

When a drug is overused or abused, the body may soon begin to develop some level of tolerance, and over time, you may not feel the effect of the drugs as much as before.

People who fall in this category may resort to taking an overdose of the drug so that they may be able to experience the same effect they are used to the feeling after taking Adderall.


A constant overdose of Adderall may lead to other adverse effects in the body.

#4 Depression may become worse during withdrawal

Since the body may quickly become used to the drug, people with depression may not get relief as much as they want to.

They could plunge further into depression and may find themselves more withdrawn from people around them and the society at large.

Such cases may also result in harmful situations to the sufferer. In this regard, you may have to find other conventional means of treating depression.

The chemistry of Adderall abuse

Excess dopamine is produced in your brain when there is an abuse of Adderall. The brain may try to strip out some dopamine receptors to ensure stability in the production of the substance.

As the dopamine receptors become reduced. You may need a higher dose to be able to experience its effect.

When Adderall wears off, you may begin to experience a feeling of depression, and this time, the feeling may be more severe than when it was before using the drug.

The Adderall crash and depression

Adderall crash refers to the group of symptoms of withdrawal concerned with Adderall for depression.

The symptoms of depression become more intense when users experience Adderall for depression crash.

You may experience the reverse effect of taking the drug. However, the symptoms, in this case, may become more severe than how it was initially.


These symptoms may be linked with the intake Adderall for depression, especially at a level of Adderall crash.

  • Insomnia

Users who may be experiencing the Adderall crash may find it difficult to sleep. The brain, which had once promoted the activity of relaxation and reduced anxiety, may instead cause Adderall users to be able to focus and have a proper sleep.

When you experience this counteractive effect after Adderall intake, it may be possible that you are experiencing the Adderall crash.

  • Unpleasant and Vivid dreams

As a direct opposite of its original intent, taking Adderall for depression may cause you to have unpleasant and Vivid dreams. Your mind may not be at rest, and you may feel very disturbed.

Sleep may be hard to come by, but if it does, it may be short and accompanied by dreams as if the individual is suffering from a severe fever.

  • Cravings for more Adderall for depression drugs

People experiencing Adderall crash may have abused the drug to an extent they may become addicted to the substance.

Anytime they experience any sign of depression, they may result in taking Adderall, thus increasing their cravings until it gets to a point where their body gets used to it.

At that point, they may not experience any positive effect of taking Adderall for depression purposes. We may say that such individuals may be experiencing Adderall crash.

  • Irritability and agitation

The reverse aspect of this symptom is that taking Adderall for depression may offer you improved focus and increased energy levels.

When the drug wears off or becomes abused, you may experience a reverse effect, including agitation and irritability.

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You may become easily agitated, and little things may seem to irritate you. These symptoms may be signs that you are experiencing Adderall crash.

  • Fatigue

People who are depressed may experience fatigue and loss of interest or zeal when participating in social activities.

Their personal life may also suffer as they may see themselves becoming less interested in meeting their immediate needs.

But during an episode of Adderall crash, you may experience these same symptoms even though you maintain continuous usage of Adderall for depression treatment.

The reason for this has been explained in previous sections. It may be wise at this stage to discontinue the use of the medication and focus on other more practical and conventional treatment of depression.

  • Anxiety or Panic

Panic and anxiety may set in when you are experiencing Adderall crash.

Instead of feeling confident and bursting with energy that you can successfully carry out a particular task, you may instead begin to feel anxious and fearful.

Panic attacks are severe symptoms of Adderall crash, which, if not checked, may lead to other damaging health issues.

  • Increase in appetite

Just like other stimulants, you may experience an increased appetite for food. You may find yourself needing to take Adderall before you can eat.

These are signs that you may be experiencing an Adderall crash.


What exactly is depression?

We have mentioned several benefits of taking Adderall for depression treatment.

We have also analyzed several effects that are associated with depression treatment using Adderall.

But what exactly is depression? And how would you know that you may be feeling depressed?

MDD (Major Depressive Disorder) or depression is known to affect your thoughts, actions, and feelings negatively.

Depression may cause you to experience emotions such as sadness or a total loss of interest in carrying out those activities that you love doing.

Depression is seen as one of the most common forms of mental health disorder globally.

Depression is prevalent, and it is believed that a significant percentage of the world population may have depression at one point in their lives.

People who are diagnosed as depressed may have shown symptoms of depression for at least two weeks.

According to the psychiatric associated in the United States (APA), the symptoms of depression includes the following:

  • Feeling of sadness or being moody.
  • An increase in fatigue or loss of energy
  • A feeling of guilt or worthlessness
  • Excessive sleepiness or insomnia 
  • Loss of pleasure or interest in partaking in activities you usually enjoy.
  • Increase in those forms of physical activities that are seen as purposeless such as pacing, wringing of the hand, slow speech, and movement, which are visible by others.
  • Changes in your appetite and weight gain or loss may not be connected to dieting.
  • Difficulty in making decisions, focusing, or thinking. 

What are the different forms of depression?

Depression may occur in different forms and are therefore classified into the following:


Persistent Depression: PDD is a persistent form of depressive disorder that may last for as long as two years, and it involves having a sad mood. It is also known as dysthymia.

Postpartum Depression: Postpartum depression is common among women and causes anxiety after a woman may have given birth between two weeks to six months.

Psychotic depression: This form of depression is often accompanied by delusions or hallucinations that may cause you to see, believe, and feel things that are not there.

Other forms of disorders include SAD, which is a seasonal and affective disorder type of Depression, PMDD, a premenstrual, or dysphoric disorder.

Frequently asked questions about Adderall for depression

People have often asked many different questions about Adderall for depression.

And most of them have no idea that taking Adderall for depression may be more of a contributing factor for depression, which is regarded as a withdrawal symptom or side effect of the stimulant drug.

Below are frequently asked questions about Adderall for depression.

How does Adderall intake contribute to Psychotic depression?

When you take Adderall for depression and abuse its usage, you may experience some psychological effects that may transcend beyond depression.

These effects are a collection of other symptoms that may affect the mind and result in psychotic behaviors such as hallucination and delusion.

In 2019, a study was carried out by the New England Journal.


It reported that about one in six hundred young adults and children with ADHD developed psychosis after being treated with stimulants such as Adderall.

What other treatment can be given for depression aside using Adderall?

Aside from making use of Adderall for depression medication, you may need to see a healthcare professional who may set you up on a detoxification program.

Instead of testing the symptoms, the program may be focused on treating the underlying cause of the depression.

What are the symptoms of Adderall overdose?

The symptoms of overdosing on Adderall include fever, depression, coma, confusion, seizures, vomiting, rapid breathing, diarrhea, stomach upset.

Does taking Adderall for depression improve mood?

Adderall may be capable of improving your mood, but it may also be capable of making you more depressed than you were before taking the drug, especially when it is abused.


Adderall for depression may be an effective treatment strategy, but it may not offer a permanent solution.

The side effects of using Adderall for treating depression are much higher than its positive effects.

It is advisable to seek professional help and proper counseling if you are depressed.

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